As part of the skin cancer screening, you will first be asked whether you have known legions that are of concern. The doctor will then examine your skin. This will require that you partially disrobe so that the skin can be examined. In the event a suspicious legion is detected, it is likely that biopsied and removed. It will be sent to dermatopathology lab where it will be examined with specialized microscopes.
Generally people with a lighter completion, light hair or eye color are more susceptible to skin cancer. Therefore it is recommended that those patients have skin cancer screening more frequently.
You can learn more about skin cancers at Skincancer.org.